Hi everyone, I started Duromine today 15mg and have felt OK on it, bit light headed/high maybe but appetite noticeably less, I am also taking 15mg of Lexapro. I have had a lot of trouble getting off Lexapro due to being very sensitive to SSRIs so am kind of stuck on it due to pretty bad serotonin withdrawal syndrome. My Dr knows all this. Anyway when I went to Pharmacy the pharmacist said that Lexapro and Duromine interact slightly and I looked it up further tonight and Duromine also releases serotonin. Now I'm scared that I won't be able to get off Duromine as well as Lexapro. Has anyone had any problems coming off Duromine when you have a sensitive to changes in Serotonin in the brain. Im not sure whether to take it again tomorrow. Im not doing any of this lightly, I need to lose over 40 kg I'm in the morbidly obese range, and have literally tried everything minus gastic bypass and sleeve surgery. Sigh, I really wanted this to work, any advice/experience ...